When CIA analyst Jack Ryan stumbles upon a suspicious series of bank transfers his search for answers pulls him from the safety of his desk job and catapults him into a deadly game of cat and mouse throughout Europe and the Middle East, with a rising terrorist figurehead preparing for a massive attack against the US and her allies.

The story of how one company triggered the worst drug epidemic in American history. Look into the epicenter of America's struggle with opioid addiction, from a distressed Virginia mining community, to the hallways of the DEA, and to the opulence of "one percenter" Big Pharma Manhattan.